Serum Selection System | Aesthetic Nerd

The Serum Selection System™

Stop asking for the best serum. Start asking what the skin biologically needs.

Let’s Reset This Conversation

I get asked all the time: “What’s the best serum for glide?”

There isn’t one.

There’s the right signal for the right biology at the right time.

I’ve built my toolbox over years based on mechanisms, not trends-and that’s why I see visible changes even after one treatment. I buy everything in one place Medpuchasing.com.

If I Had to Pick Just Two

I would pick the two safest products I’m aware of:

1. Liquid PDO (Renveau) → Structure + collagen stimulation

2. Growth Factors (Skingenuity) → Repair + healing amplification

Simple: one builds, one heals.

My Rule of Thumb

Base: Liquid PDO (structure)

I always use A Total Volume: ~3ml

Add: ONE targeted serum depending on biology

Example Think: 2ml structure + 1ml targeted signal

Why Cocktails Work (This Is Where Results Speed Up)

One signal = progress. Multiple correct signals = acceleration.

Skin doesn’t heal in a straight line-it responds to layers of communication.

  • Structure tells skin what to rebuild
  • Growth factors tell it how fast to repair
  • Exosomes tell it how to behave
  • Peptides support function and stability

When you combine the right signals, you reduce guesswork and increase speed of visible change.

How I Categorize My Toolbox

STRUCTURE + COLLAGEN

  • Liquid PDO (Renveau) largest collagen production
  • Cod-Lagen (promoitalia)

Easy version:

Builds the “scaffolding” of your skin.

Science: stimulates fibroblasts → collagen + elastin.

REPAIR + HEALING

  • Growth Factors (Skingenuity)
  • Tendu PN-HA
  • Nucleoskin (PDRN)
  • Procell MD Serum

Easy version:

Helps skin recover faster and stronger.

Science: improves cellular repair, reduces inflammation.

CELLULAR COMMUNICATION

  • Exosomes (EVOA)
  • V-Hacker
  • Upgrade (Promoitalia)

Easy version:

Tells your cells how to act younger.

Science: signaling molecules guide regeneration + behavior.

HYDRATION + FINISHING

  • Skinfill Blue
  • Pure HA

Easy version:

Adds water, bounce, and smoothness.

Science: HA binds water → improves elasticity.

PIGMENT + CORRECTION

  • White In
  • LC Bright
  • LC TX

Easy version:

Balances uneven tone.

Science: regulates melanocytes + pigment pathways.

HAIR + SCALP

  • Exosignal Hair
  • LC Hair
  • V-Hacker

Easy version:

Supports stronger, healthier hair growth.

Science: improves follicle signaling + circulation.

Skin Changes… So Should Your Approach

  • Inflamed skin → lean repair
  • Aging skin → lean structure
  • Dull skin → add communication signals
  • Dehydrated skin → increase HA support

Your protocol should evolve as the skin improves.

Why This Works

Skin doesn’t respond to hype. It responds to signals.

Different biology = different signal = different outcome.

Final Thought

I have access to a wide selection—but I don’t use everything on everyone.

I simplify it:

Build with PDO. Repair with growth factors. Then customize.

This isn’t about glide.

This is regenerative decision-making.